Yamamoto S, Kamiyama M, Nitta K, Yamada T, Hayasaka S
Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
Br J Ophthalmol. 1996 Nov;80(11):973-5. doi: 10.1136/bjo.80.11.973.
To determine whether the short wavelength sensitive (S) cone electroretinogram (ERG) is selectively altered in diabetic patients with and without retinopathy.
Ganzfeld spectral flashes in the presence of bright white background illumination were used to elicit S cone ERGs is 15 non-retinopathic diabetics, 16 background retinopathic diabetics, and 16 age matched normal controls.
The amplitude of the S cone ERG b-wave was significantly reduced in both non-retinopathic and retinopathic diabetics. An action spectrum based on equal response criteria revealed a selective loss of S cone sensitivity in diabetics. However, no significant difference was observed in the long and middle wavelength sensitive cone ERG.
Diabetic patients showed selective reduction of the S cone ERG, which is thought to reflect changes in the outer retina.
确定患有和未患有视网膜病变的糖尿病患者中短波长敏感（S）视锥细胞视网膜电图（ERG）是否有选择性改变。
在明亮白色背景照明下使用全视野光谱闪光，对15名无视网膜病变的糖尿病患者、16名背景性视网膜病变糖尿病患者和16名年龄匹配的正常对照者进行S视锥细胞ERG检测。
无视网膜病变和有视网膜病变的糖尿病患者中，S视锥细胞ERG的b波振幅均显著降低。基于相等反应标准的作用光谱显示糖尿病患者中S视锥细胞敏感性有选择性丧失。然而，在长波长和中波长敏感视锥细胞ERG中未观察到显著差异。
糖尿病患者表现出S视锥细胞ERG的选择性降低，这被认为反映了视网膜外层的变化。
