从血清中去除氨基糖苷类以允许对其他抗菌剂进行生物测定的简单方法。
Simple method for elimination of aminoglycosides from serum to permit bioassay of other antimicrobial agents.
作者信息
Stevens P, Young L S
出版信息
Antimicrob Agents Chemother. 1977 Aug;12(2):286-7. doi: 10.1128/AAC.12.2.286.
Abstract
Cellulose phosphate powder can be added to serum to selectively bind aminoglycosides by ionic interaction without binding or inactivation of the penicillins, the cephalosporins, clindamycin, vancomycin, chloramphenicol, or trimethoprim. This simple, rapid technique permits the measurement of non-aminoglycoside antibiotics in the presence of aminoglycosides.
摘要
磷酸纤维素粉末可添加到血清中，通过离子相互作用选择性结合氨基糖苷类药物，而不会使青霉素、头孢菌素、克林霉素、万古霉素、氯霉素或甲氧苄啶结合或失活。这种简单、快速的技术可在氨基糖苷类药物存在的情况下测定非氨基糖苷类抗生素。
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J Infect Dis. 1971 Dec;124 Suppl:S90-5. doi: 10.1093/infdis/124.supplement_1.s90.
2
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J Lab Clin Med. 1971 Sep;78(3):457-63.
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