淋巴细胞质膜脂质双层中细胞表面抗原的取向
Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane.
作者信息
Walsh F S, Crumpton M J
出版信息
Nature. 1977 Sep 22;269(5626):307-11. doi: 10.1038/269307a0.
DOI:10.1038/269307a0
PMID:904685
Abstract
Human HLA-A, B, C and Ia antigens were labelled by lactoperoxidase-catalysed iodination of the inner surface of lymphocyte plasma membrane and thus are transmembrane proteins. In contrast, membrane-bound human IgM and mouse IgM, IgD and Thy-1 antigen were not labelled on the inner membrane surface.
摘要
通过乳过氧化物酶催化淋巴细胞质膜内表面碘化标记人HLA - A、B、C和Ia抗原，因此它们是跨膜蛋白。相比之下，膜结合的人IgM和小鼠IgM、IgD及Thy - 1抗原在内膜表面未被标记。
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