Akasaka T, Imamura Y, Mori Y, Iwasaki M, Kon S
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
J Dermatol. 1997 Mar;24(3):174-8. doi: 10.1111/j.1346-8138.1997.tb02767.x.
The following is a case study of a 36-year-old Japanese man with a trichoblastoma which exhibited a rippled-pattern on the left temporal region of the scalp. The histological findings of the tumor revealed lobular aggregations composed of immature follicular basaloid cells, lobules of squamous eddy-like foci of incomplete keratinization or small keratinous cysts, and multiple papillary mesenchymal bodies similar to hair germ. Interestingly, a rippled-pattern of basaloid cells and hyalinized matrixes resembling the Verocay bodies of neurilemmoma was also observed. We propose that the rippled-pattern of the basaloid cells and hyalinized matrices is caused by the characteristic stromal induction of trichoblastoma.
以下是一名36岁日本男性的病例研究，其头皮左颞部患有毛母细胞瘤，呈现出波纹状形态。肿瘤的组织学检查结果显示，由未成熟毛囊基底样细胞组成的小叶聚集、不完全角化的鳞状涡状灶或小角质囊肿小叶，以及多个类似于毛胚的乳头状间充质体。有趣的是，还观察到基底样细胞的波纹状形态和类似于神经鞘瘤Verocay小体的透明化基质。我们认为，基底样细胞和透明化基质的波纹状形态是由毛母细胞瘤的特征性基质诱导所致。
