Andersen H C, Andersen I, Solgaard J
Br J Ind Med. 1977 Aug;34(3):201-7. doi: 10.1136/oem.34.3.201.
In 186 cases of nasal cancer diagnosed over the decade 1965-74, in a population of 2-0 million, 114 of 157 ectodermal tumours were found in men. Adenocarcinoma was found in 17 patients, two women and 15 men; 12 of these had a history of occupational exposure to wood dust in the furniture industry. The period of latency was from 28 to 57 years. Among the remaining 99 tumours in men there was occupational exposure to wood dust in 10 cases. Wood dust concentrations in the breathing zone, respiratory symptoms and upper airway function were studied in 68 workers in the furniture industry. The dust concentrations affecting 63% of the workers were higher than 5 mg/m3 (TLV). Middle ear inflammation and common colds were more frequent at high dust concentrations, and the number of workers with nasal mucostasis was directly proportional to the wood dust concentration.
在1965年至1974年这十年间确诊的186例鼻癌病例中,在200万人口中,157例外胚层肿瘤中有114例发生在男性身上。17例患者被诊断为腺癌,其中2名女性和15名男性;这些患者中有12人有在家具行业职业接触木尘的病史。潜伏期为28至57年。在其余99例男性肿瘤病例中,有10例存在职业性木尘接触史。对家具行业的68名工人进行了呼吸带木尘浓度、呼吸道症状和上呼吸道功能的研究。影响63%工人的粉尘浓度高于5毫克/立方米(阈限值)。高粉尘浓度时中耳炎和普通感冒更为常见,鼻黏膜停滞的工人数量与木尘浓度成正比。