中国苯接触工人癌症的一项扩大队列研究。苯研究组。
An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group.
作者信息
Yin S N, Hayes R B, Linet M S, Li G L, Dosemeci M, Travis L B, Zhang Z N, Li D G, Chow W H, Wacholder S, Blot W J
机构信息
Chinese Academy of Preventive Medicine, Bejing, China.
出版信息
Environ Health Perspect. 1996 Dec;104 Suppl 6(Suppl 6):1339-41. doi: 10.1289/ehp.961041339.
Abstract
An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.
摘要
基于此前在中国12个城市开展的一项研究，1972年至1987年期间对74,828名接触苯的工人和35,805名未接触苯的工人进行了一项扩大队列研究。与未接触苯的工人相比，接触苯的工人的总癌症死亡率略有上升（相对风险[RR]=1.2）。白血病（RR=2.3）、恶性淋巴瘤（RR=4.5）和肺癌（RR=1.4）的统计学显著超额死亡率被记录下来。当按白血病亚型评估风险时，只有急性髓细胞白血病显著升高（RR=3.1），尽管慢性髓细胞白血病（RR=2.6）和急性淋巴细胞白血病（RR=2.3）也有非显著的超额死亡率。再生障碍性贫血也有显著超额死亡率。
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