Buchner H, Knoll G, Fuchs M, Rienäcker A, Beckmann R, Wagner M, Silny J, Pesch J
Department of Neurology, RWTH, Aachen, Germany.
Electroencephalogr Clin Neurophysiol. 1997 Apr;102(4):267-78. doi: 10.1016/s0013-4694(96)95698-9.
The paper describes finite element related procedures for inverse localization of multiple sources in realistically shaped head models. Dipole sources are modeled by placing proper monopole sources on neighboring nodes. Lead field operators are established for dipole sources. Two different strategies for the solution of inverse problems, namely combinatorial optimization techniques and regularization methods are discussed and applied to visually evoked potentials, for which exemplary results are shown. Most of the procedures described are fully automatic and require only proper input preparation. The overall work for the example presented (from EEG recording to visual inspection of the results) can be performed in roughly a week, most of which is waiting time for the computation of the lead field matrix or inverse calculations on a standard and affordable engineering workstation.
本文描述了在逼真形状的头部模型中对多个源进行逆定位的有限元相关程序。通过在相邻节点上放置适当的单极源来模拟偶极源。为偶极源建立导联场算子。讨论了两种求解逆问题的不同策略，即组合优化技术和正则化方法，并将其应用于视觉诱发电位，给出了示例结果。所描述的大多数程序都是全自动的，只需要适当的输入准备。所举示例的整体工作（从脑电图记录到结果的目视检查）大约一周即可完成，其中大部分是在标准且价格合理的工程工作站上计算导联场矩阵或进行逆计算的等待时间。
