Telford S R, Armstrong P M, Katavolos P, Foppa I, Garcia A S, Wilson M L, Spielman A
Harvard School of Public Health, Boston, Massachusetts, USA.
Emerg Infect Dis. 1997 Apr-Jun;3(2):165-70. doi: 10.3201/eid0302.970209.
To determine if eastern North American Ixodes dammini, like related ticks in Eurasia, maintain tick-borne encephalitis group viruses, we analyzed ticks collected from sites where the agent of Lyme disease is zoonotic. Two viral isolates were obtained by inoculating mice with homogenates from tick salivary glands. The virus, which was described by reverse transcriptase polymerase chain reaction and direct sequencing of the amplification products, was similar to, but distinct from, Powassan virus and is provisionally named "deer tick virus." Enzootic tick-borne encephalitis group viruses accompany the agents of Lyme disease, babesiosis, and granulocytic ehrlichiosis in a Holarctic assemblage of emergent deer tick pathogens.
为了确定北美东部的达氏硬蜱(Ixodes dammini)是否像欧亚大陆的相关蜱虫那样携带着蜱传脑炎病毒群病毒,我们分析了从莱姆病病原体为人畜共患病原体的地点采集的蜱虫。通过用蜱虫唾液腺匀浆接种小鼠,获得了两种病毒分离株。通过逆转录聚合酶链反应和对扩增产物进行直接测序来描述的这种病毒,与波瓦桑病毒相似但又不同,暂命名为“鹿蜱病毒”。在一个全北区新出现的鹿蜱病原体组合中,蜱传脑炎病毒群病毒与莱姆病、巴贝斯虫病和粒细胞埃立克体病的病原体共存。