Kauppinen T, Teschke K, Savela A, Kogevinas M, Boffetta P
Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, Helsinki, Finland.
Int Arch Occup Environ Health. 1997;70(2):119-27. doi: 10.1007/s004200050195.
An international data base of exposure measurements in the pulp, paper and paper product industries was constructed to be used in exposure assessment for epidemiology studies and hazard control. Industrial hygiene and biological monitoring data were collected from countries participating in the multicentric study of the International Agency for Research on Cancer. Each measurement was characterized by country, mill type and number, department, job, agent measured, sampling method, measurement result in the standard unit, duration and date of sampling, assessment of representativeness, measurer, purpose of measurements, and remarks (e.g. on measurement sites and biases). Over 31,000 measurement results on 246 different chemical agents from 13 countries were available from pulp (45% of measurements), paper/paperboard/recycling (12%) and paper product (11%) mills or from their non-production departments (23%). Most measurements (82%) were carried out after 1980. The most frequently measured group of agents was inorganic gases (35%), followed by organic compounds (25%), solvents (18%), mineral dusts (12%), metals (6%) and bioaerosols (3%). Over 90% of the measurements were without an obvious bias, but their true representativeness is difficult to assess. Concentrations of various agents, including sulfur dioxide, chlorine dioxide, carbon monoxide, nitrogen dioxide, ozone, ammonia, formaldehyde and some solvents, often exceeded current occupational exposure limits. This data base summarizes a great deal of previously unpublished exposure data, provides a unique opportunity to study exposure patterns at the international level and identifies exposure situations that require further attention and investigation.
建立了一个纸浆、造纸及纸制品行业暴露测量的国际数据库,用于流行病学研究的暴露评估和危害控制。工业卫生和生物监测数据收集自参与国际癌症研究机构多中心研究的国家。每次测量的特征包括国家、工厂类型和编号、部门、工作、测量的试剂、采样方法、标准单位的测量结果、采样持续时间和日期、代表性评估、测量者、测量目的以及备注(如测量地点和偏差)。来自纸浆厂(占测量的45%)、造纸/纸板/回收厂(12%)、纸制品厂(11%)或其非生产部门(23%),涉及13个国家的246种不同化学试剂的31000多个测量结果可供使用。大多数测量(82%)是在1980年以后进行的。测量最频繁的试剂组是无机气体(35%),其次是有机化合物(25%)、溶剂(18%)、矿物粉尘(12%)、金属(6%)和生物气溶胶(3%)。超过90%的测量没有明显偏差,但其真实代表性难以评估。包括二氧化硫、二氧化氯、一氧化碳、二氧化氮、臭氧、氨、甲醛和一些溶剂在内的各种试剂的浓度经常超过当前职业暴露限值。该数据库总结了大量以前未发表的暴露数据,提供了在国际层面研究暴露模式的独特机会,并确定了需要进一步关注和调查的暴露情况。