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亚速尔群岛分离出致病性钩端螺旋体的首批流行病学数据。

First epidemiological data on pathogenic leptospires isolated on the Azorean islands.

作者信息

Collares-Pereira M, Korver H, Terpstra W J, Santos-Reis M, Ramalhinho M G, Mathias M L, Oom M M, Fons R, Libois R, Petrucci-Fonseca F

机构信息

Laboratório de Leptospiras, Universidade Nova de Lisboa, Portugal.

出版信息

Eur J Epidemiol. 1997 Jun;13(4):435-41. doi: 10.1023/a:1007383405833.

DOI:10.1023/a:1007383405833
PMID:9258550
Abstract

Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores Archipelago were found to carry three distinct Leptospira interrogans s.l. serovars (copenhageni, icterohaemorrhagiae and ballum) which have never been previously investigated there. The house mouse and the black rat were the major Leptospira reservoirs showing isolation rates ranging from 0% for both species (in Graciosa) to 88% and 33%, respectively (in Sãao Miguel). This study also showed that the majority of the animals with positive kidney cultures exhibited specific agglutinins against the isolated strains of Leptospira. The observed isolation rates in the different islands, with a very interesting island variation in prevalence, suggest that small mammals, serving as sylvatic reservoirs of pathogenic leptospires, may represent an important risk to the health of humans and livestock, particularly in the islands of Terceira and Sãao Miguel.

摘要

在亚速尔群岛不同岛屿上发现,食虫动物(欧洲刺猬)和啮齿动物(黑家鼠、褐家鼠和小家鼠)携带三种不同的问号状钩端螺旋体血清型(哥本哈根型、黄疸出血型和拜伦型),此前在该地区从未对其进行过调查。家鼠和黑家鼠是主要的钩端螺旋体宿主,隔离率从两种物种在格拉西奥萨岛的0%到圣米格尔岛的88%和33%不等。这项研究还表明,大多数肾脏培养呈阳性的动物对分离出的钩端螺旋体菌株表现出特异性凝集素。在不同岛屿上观察到的隔离率以及患病率中非常有趣的岛屿差异表明,作为致病性钩端螺旋体野生宿主的小型哺乳动物可能对人类和牲畜的健康构成重大风险,尤其是在特塞拉岛和圣米格尔岛。

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