Nagai H, Yasumoto T, Hokama Y
Suntory Institute for Bioorganic Research, Osaka, Japan.
J Nat Prod. 1997 Sep;60(9):925-8. doi: 10.1021/np970193c.
Manauealides A-C (1-3), compounds related to debromoaplysiatoxin (5), were isolated and characterized from a red alga Gracilaria coronopifolia. Compounds 1 and 2 are presumed to be the causative toxins of G. coronopifolia food poisoning in Hawaii. Manauealide A (1) and C (3) are new macrolides, whereas manauealide B (2) is a known semisynthetic product of 5.
从红藻龙须菜中分离并鉴定出与脱溴海兔毒素(5)相关的化合物马纳韦利德A - C(1 - 3)。化合物1和2被认为是夏威夷龙须菜食物中毒的致病毒素。马纳韦利德A(1)和C(3)是新的大环内酯类化合物,而马纳韦利德B(2)是已知的5的半合成产物。