Puapermpoonsiri S, Watanabe K, Kato N, Ueno K
Department of Clinical Microbiology, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand.
Antimicrob Agents Chemother. 1997 Oct;41(10):2297-9. doi: 10.1128/AAC.41.10.2297.
The in vitro activities of 10 antimicrobial agents against 159 bacterial vaginosis-associated anaerobic isolates from pregnant Japanese and Thai women were determined. Clindamycin, imipenem, cefmetazole, amoxicillin, amoxicillin-clavulanate, and metronidazole were highly active against all anaerobic isolates except Prevotella bivia and Mobiluncus species, which were resistant to amoxicillin and metronidazole, respectively. Cefotiam, ceftazidime, and ofloxacin were variably effective, while cefaclor was the least effective agent.
测定了10种抗菌药物对159株来自日本和泰国孕妇的细菌性阴道病相关厌氧分离株的体外活性。克林霉素、亚胺培南、头孢美唑、阿莫西林、阿莫西林-克拉维酸和甲硝唑对所有厌氧分离株均具有高活性,但二路普雷沃菌和动弯杆菌属除外,它们分别对阿莫西林和甲硝唑耐药。头孢替安、头孢他啶和氧氟沙星的效果不一,而头孢克洛是效果最差的药物。