Ershoff B H
Proc Soc Exp Biol Med. 1976 Jun;152(2):253-6. doi: 10.3181/00379727-152-39373.
Immature male rats were fed a purified, low-fiber diet containing massive doses of sodium cyclamate or amaranth (FD and C Red No. 2). Sodium cyclamate when incorporated at a 5% level in the purified, low-fiber diet resulted in toxic manifestations which were counteracted by the concurrent administration of the anion exchange resin cholestyramine at a 2 1/2% level in the diet. Other anion exchange resins were also active in this regard. Cholestyramine at a 2 1/2% level of supplementation was also active in counteracting the toxic effects induced by amaranth when the latter was incorporated at a 5% level in the purified, low-fiber diet.
给未成熟雄性大鼠喂食一种纯化的低纤维饮食，其中含有大剂量的甜蜜素或苋菜红（食用红色素2号）。当甜蜜素以5%的比例添加到纯化的低纤维饮食中时，会产生毒性表现，而在饮食中同时添加2.5%的阴离子交换树脂消胆胺可抵消这些毒性表现。其他阴离子交换树脂在这方面也有活性。当苋菜红以5%的比例添加到纯化的低纤维饮食中时，补充2.5%的消胆胺也能有效抵消其诱导的毒性作用。
