Adlouni A, Ghalim N, Benslimane A, Lecerf J M, Saile R
Département de Biologie, Faculté des Sciences Ben M'sik, Casablanca, Morocco.
Ann Nutr Metab. 1997;41(4):242-9. doi: 10.1159/000177999.
We demonstrated for the first time in a Moroccan population that fasting during Ramadan, the ninth lunar month of the Muslims' year, affected lipid and lipoprotein metabolism in a group of 32 healthy adult male volunteers. This investigation was conducted to study the changes in serum total cholesterol, triglycerides, cholesterol in high-density lipoprotein (HDL) and low-density lipoprotein (LDL), glucose, and body weight during Ramadan. The results showed a significant decrease (7.9%, p < 0.001) in serum total cholesterol concentration during Ramadan as compared with the prefasting period. Also, we obtained a significant decrease of serum triglyceride concentration (30%, p < 0.001) during Ramadan fasting as compared to the period before Ramadan. The reduction of both serum triglycerides and total cholesterol was maintained 1 month after Ramadan. By the end of Ramadan, serum HDL cholesterol had markedly increased (14.3%, p < 0.001) and remained elevated 1 month after Ramadan in contrast to LDL cholesterol which showed a significant decrease (11.7%, p < 0.0001) also maintained 1 month after Ramadan. Mean body weight declined by 2.6% (p < 0.01) on day 29 of Ramadan, whereas during Ramadan, the diet pattern used by our subjects showed an increase of total energy intake due to carbohydrates (+ 1.4% of total energy), proteins (+ 0.4% of total energy) but not fat (-0.7% of total energy) compared to a usual diet used throughout the rest of the year. Moreover, the fat diet is high in monounsaturated (p < 0.05) and polyunsaturated fatty acid in contrast to saturated fatty acid which significantly (p < 0.05) decreased during Ramadan. These findings suggest that feeding behavior that occurs during Ramadan beneficially affects plasma lipids and lipoproteins.
我们首次在摩洛哥人群中证明，斋月（穆斯林一年中的第九个农历月）期间禁食对一组32名健康成年男性志愿者的脂质和脂蛋白代谢产生了影响。本次调查旨在研究斋月期间血清总胆固醇、甘油三酯、高密度脂蛋白（HDL）和低密度脂蛋白（LDL）中的胆固醇、葡萄糖及体重的变化。结果显示，与禁食前相比，斋月期间血清总胆固醇浓度显著降低（7.9%，p<0.001）。此外，与斋月前相比，斋月禁食期间血清甘油三酯浓度显著降低（30%，p<0.001）。斋月结束后1个月，血清甘油三酯和总胆固醇的降低仍持续存在。斋月结束时，血清HDL胆固醇显著升高（14.3%，p<0.00），并在斋月结束后1个月保持升高，而LDL胆固醇则显著降低（11.7%，p<0.0001），且在斋月结束后1个月也持续降低。斋月第29天时，平均体重下降了2.6%（p<0.01），而在斋月期间，我们的受试者采用的饮食模式显示，与全年其他时间的日常饮食相比，碳水化合物导致总能量摄入增加（占总能量的+1.4%），蛋白质导致总能量摄入增加（占总能量的+0.4%），但脂肪导致总能量摄入减少（占总能量-0.7%）。此外，与饱和脂肪酸在斋月期间显著降低（p<0.05）相反，脂肪饮食中的单不饱和脂肪酸（p<0.05）和多不饱和脂肪酸含量较高。这些发现表明，斋月期间的进食行为对血浆脂质和脂蛋白有有益影响。
