Maislos M, Abou-Rabiah Y, Zuili I, Iordash S, Shany S
Department of Medicine, Toor Institute, Israel.
Eur J Clin Nutr. 1998 Feb;52(2):127-30. doi: 10.1038/sj.ejcn.1600526.
To evaluate the effect of a single evening meal (gorging) on plasma lipids and lipoproteins in normal individuals observing the Ramadan Fast. During the Ramadan month, Muslims refrain from food and liquids during the day and eat a large meal after sundown.
Sequential measurement of plasma lipids and lipoproteins in Muslims observing the Ramadan Fast and non-fasting individuals.
The study was conducted in the Bedouin town of Rahat, in the northern Negev area of Israel.
Twenty-two healthy subjects who fasted during Ramadan and 16 non-fasting laboratory workers, were studied before Ramadan, at week 1, 2 and 4 of the Ramadan month, and again four weeks after the end of Ramadan.
Plasma high-density lipoprotein cholesterol (HDL) rose significantly (P < 0.001) at the week 4 measurement, returning to basal levels 4 weeks after the end of Ramadan. Total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL), very-low density lipoprotein cholesterol (VLDL), and lipoprotein (a) [Lp(a)] did not change significantly.
Plasma HDL increased by 23% after four weeks of gorging. The dietary change did not affect the composition of other lipoproteins, such as LDL, VLDL or Lp(a), other plasma biochemical parameters, or BMI. Prolonged gorging, well tolerated by all individuals, is a very effective non-pharmacological method to increase plasma HDL-cholesterol.
评估在斋月禁食期间正常个体单次晚餐暴饮暴食对血浆脂质和脂蛋白的影响。在斋月期间，穆斯林白天禁食禁水，日落后进食大餐。
对斋月禁食的穆斯林和非禁食个体的血浆脂质和脂蛋白进行连续测量。
该研究在以色列内盖夫北部地区的贝都因城镇拉哈特进行。
22名斋月期间禁食的健康受试者和16名非禁食的实验室工作人员，在斋月前、斋月第1周、第2周和第4周以及斋月结束后四周进行研究。
在第4周测量时，血浆高密度脂蛋白胆固醇（HDL）显著升高（P < 0.001），斋月结束后4周恢复至基础水平。总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL）、极低密度脂蛋白胆固醇（VLDL）和脂蛋白（a）[Lp（a）]无显著变化。
暴饮暴食四周后血浆HDL升高23%。饮食变化未影响其他脂蛋白的组成，如LDL、VLDL或Lp（a），也未影响其他血浆生化参数或体重指数（BMI）。所有个体对长期暴饮暴食耐受性良好，这是一种增加血浆HDL胆固醇的非常有效的非药物方法。
