实体器官移植后巨细胞病毒的监测：pp65抗原血症检测与定量DNA杂交检测的比较
Surveillance of cytomegalovirus after solid-organ transplantation: comparison of pp65 antigenemia assay with a quantitative DNA hybridization assay.
作者信息
Bossart W, Bienz K, Wunderli W
机构信息
Institute of Medical Virology, University of Zurich, Switzerland.
出版信息
J Clin Microbiol. 1997 Dec;35(12):3303-4. doi: 10.1128/jcm.35.12.3303-3304.1997.
Abstract
In a multicenter study, 113 blood samples from 19 organ transplant patients were analyzed for cytomegalovirus by the pp65 antigenemia assay and a quantitative DNA hybridization assay. Overall, there was 84% agreement among the results obtained by the two tests. Fifteen of 16 episodes of active infection were detected by both assays. One episode was missed by the pp65 assay, and one patient showed significant DNA-emia but only low-level antigenemia.
摘要
在一项多中心研究中，采用pp65抗原血症检测法和定量DNA杂交检测法对19例器官移植患者的113份血样进行了巨细胞病毒分析。总体而言，两种检测方法所得结果的一致性为84%。两种检测方法均检测出了16例活动性感染中的15例。pp65检测法漏检了1例，1例患者显示出显著的DNA血症，但仅有低水平的抗原血症。
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