Concanavalin A cap formation on human polymorphonuclear leukocytes induced by R17934, a new antitumor drug that interferes with microtubule assembly.
作者信息
Oliver J M
出版信息
J Reticuloendothel Soc. 1976 Jun;19(6):389-95.
PMID:940091
Abstract
摘要
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The effects of methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl) carbamate, (R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro.新型合成抗肿瘤药物甲基（5-（2-噻吩基羰基）-1H-苯并咪唑-2-基）氨基甲酸酯（R 17934；NSC 238159）对体外培养的哺乳动物细胞的影响，该药物可干扰微管。
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Stimulation of plasminogen activator expression and induction of DNA synthesis by microtubule-disruptive drugs.微管破坏药物对纤溶酶原激活物表达的刺激作用及对DNA合成的诱导作用。
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Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes.伴刀豆球蛋白A可诱导人多形核白细胞中的微管组装和特定颗粒释放。
J Cell Biol. 1976 Mar;68(3):781-7. doi: 10.1083/jcb.68.3.781.
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A correlation between in vivo and in vitro effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on myxamoebae of Physarum polycephalum.微管抑制剂秋水仙碱、巴苯哒唑和诺考达唑对多头绒泡菌变形体的体内和体外效应之间的相关性。
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Oncodazole (R 17934) an inhibitor of the turnover of phosphatidyl inositol in concanavalin A induced lymphocytes.
Biochem Pharmacol. 1979 Oct 1;28(19):2967-8. doi: 10.1016/0006-2952(79)90594-x.
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Polarization of endocytosis and receptor topography on cultured macrophages.培养巨噬细胞内吞作用的极化及受体拓扑结构
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Microtubule assembly and conanavalin A capping in lymphocytes: reappraisal using normal and abnormal human peripheral blood cells.
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Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence.与高分子量表面糖蛋白（GP138）遗传性缺乏相关的多形核白细胞功能异常：与细胞黏附减少的共同关系。
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Electrokinetic response of granulocytes to concanavalin A and succinyl-concanavalin A.粒细胞对伴刀豆球蛋白A和琥珀酰伴刀豆球蛋白A的电动响应。
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Effects of glutathione-oxidizing agents on microtubule assembly and microtubule-dependent surface properties of human neutrophils.谷胱甘肽氧化剂对人中性粒细胞微管组装及微管依赖表面特性的影响
J Cell Biol. 1976 Dec;71(3):921-32. doi: 10.1083/jcb.71.3.921.
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Analogous ultrastructure and surface properties during capping and phagocytosis in leukocytes.白细胞中封闭和吞噬过程中的类似超微结构及表面特性。
J Cell Biol. 1978 Jun;77(3):789-804. doi: 10.1083/jcb.77.3.789.
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Microtubules and cyclic AMP in human leukocytes: on the order of things.人白细胞中的微管与环磷酸腺苷：关于事物的顺序
J Cell Biol. 1978 Jun;77(3):881-6. doi: 10.1083/jcb.77.3.881.
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Impaired microtubule function correctable by cyclic GMP and cholinergic agonists in the Chediak-Higashi syndrome.在切-东综合征中，微管功能受损可通过环磷酸鸟苷和胆碱能激动剂纠正。
Am J Pathol. 1976 Nov;85(2):395-418.
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