Espinoza R, Vial P, Noriega L M, Johnson A, Nichol S T, Rollin P E, Wells R, Zaki S, Reynolds E, Ksiazek T G
Clinica Alemana de Santiago, Chile.
Emerg Infect Dis. 1998 Jan-Mar;4(1):93-5. doi: 10.3201/eid0401.980112.
A case of hantavirus pulmonary syndrome (HPS) was serologically confirmed in a critically ill patient in Santiago, Chile. The patient's clinical course had many similarities to that of other HPS patients in North and South America but was complicated by acute severe renal failure. The patient's history included self-reported urban and probable rural rodent exposure during travel in Bolivia. Comparison of a viral sequence from an acute-phase serum sample with other known hantaviruses showed that the hantavirus nucleic acid sequence from the patient was very similar to a virus recently isolated from rodents associated with HPS cases in Paraguay.
智利圣地亚哥一名重症患者经血清学确诊感染汉坦病毒肺综合征(HPS)。该患者的临床病程与北美和南美其他HPS患者有许多相似之处,但并发了急性严重肾衰竭。患者自述在玻利维亚旅行期间有城市和可能的农村啮齿动物接触史。将急性期血清样本中的病毒序列与其他已知汉坦病毒进行比较,结果显示该患者的汉坦病毒核酸序列与最近从巴拉圭与HPS病例相关的啮齿动物中分离出的一种病毒非常相似。