Liu G G
Department of Pharmaceutical Economics and Policy, University of Southern California, Los Angeles 90033, USA.
Health Serv Res. 1998 Feb;32(6):805-23.
To investigate pregnant women's self-selection effects on the estimation of birthweight production function. A particular emphasis is placed on assessing the effectiveness of prenatal care as a major medical input in the birthweight production function.
Primary data compiled from birth and abortion certificates for the Commonwealth of Virginia in 1984. Several area-specific socioeconomic variables were also employed from the Area Resource File 1984; Supplemental Food Program for Women, Infants, and Children (WIC) Local Agency Directory; and the family planning clinics data by the Alan Guttmacher Institute (AGI).
Two types of self-selection effects are defined: selection effect due to sample censoring from the resolution of pregnancies as live births or induced abortions; and selection effect due to the use of prenatal care as an endogenous variable. Race- and location-specific birthweight production functions are estimated using models with and without correction for self-selection effects.
The self-selection effect in the resolution of pregnancies is race-specific, being significant for African American women. The effectiveness of prenatal care in birthweight production is underestimated substantially by the selection bias from the use of prenatal care, and overestimated by the selection bias from pregnancy resolutions. On average, the overall estimated effectiveness of prenatal care is over five times higher after controlling for the selection effects.
Self-selection effects could be a very serious problem in measuring the effectiveness of birthweight determinants in general. The overall effectiveness of prenatal care, in particular, tends to be significantly biased downward without controlling for selection effects. The significance and scale of the bias depends crucially on specific data and cohorts of the population investigated.
研究孕妇的自我选择对出生体重生产函数估计的影响。特别强调评估产前护理作为出生体重生产函数中主要医疗投入的有效性。
1984年弗吉尼亚联邦州出生和流产证明汇编的原始数据。还采用了1984年区域资源文件中的几个特定地区社会经济变量;妇女、婴儿和儿童补充食品计划(WIC)地方机构名录;以及艾伦·古特马赫研究所(AGI)的计划生育诊所数据。
定义了两种类型的自我选择效应:因怀孕结局为活产或人工流产导致样本审查产生的选择效应;以及因将产前护理作为内生变量使用产生的选择效应。使用考虑和不考虑自我选择效应校正的模型估计种族和地区特定的出生体重生产函数。
怀孕结局中的自我选择效应因种族而异,对非裔美国女性显著。产前护理在出生体重生产中的有效性因使用产前护理的选择偏差而被大幅低估,因怀孕结局的选择偏差而被高估。平均而言,在控制选择效应后,产前护理的总体估计有效性高出五倍多。
一般来说,自我选择效应在衡量出生体重决定因素的有效性方面可能是一个非常严重的问题。特别是,如果不控制选择效应,产前护理的总体有效性往往会被显著低估。偏差的显著性和规模关键取决于所调查人群的具体数据和队列。