台湾的莱姆病：首例出现特征性慢性游走性红斑皮肤损害的人类患者。
Lyme disease in Taiwan: first human patient with characteristic erythema chronicum migrans skin lesion.
作者信息
Shih C M, Wang J C, Chao L L, Wu T N
机构信息
Department of Parasitology and Tropical Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
出版信息
J Clin Microbiol. 1998 Mar;36(3):807-8. doi: 10.1128/JCM.36.3.807-808.1998.
Abstract
We report herein the first laboratory-diagnosed case of Lyme disease in a human in Taiwan. A 45-year-old Taiwanese man living in Taipei, in northern Taiwan, had an expanding skin lesion (measuring 23 by 15 cm) on his abdomen for 2 to 3 weeks and recurrent attacks of pain and swelling of the knee joint. Serologic tests indicated a significantly elevated titer of antibody to Borrelia burgdorferi. After appropriate antibiotic treatment for 3 weeks, the skin lesion was cured and the joint swelling was improved. Although several strains of Borrelia spirochetes had been isolated from rodents (Rattus losea) in Taiwan, the tick vector responsible for the transmission remains to be identified.
摘要
我们在此报告台湾首例经实验室确诊的人类莱姆病病例。一名居住在台湾北部台北市的45岁台湾男性，其腹部有一处不断扩大的皮肤损伤（尺寸为23×15厘米），持续了2至3周，并且膝关节反复出现疼痛和肿胀。血清学检测显示抗伯氏疏螺旋体抗体滴度显著升高。经过3周的适当抗生素治疗后，皮肤损伤治愈，关节肿胀有所改善。尽管在台湾已从啮齿动物（斯氏家鼠）中分离出几种疏螺旋体菌株，但负责传播的蜱媒仍有待确定。
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