Shadaba A, Gaze M N, Grant H R
Royal National Throat, Nose and Ear Hospital, London, UK.
J Laryngol Otol. 1997 Dec;111(12):1186-9. doi: 10.1017/s0022215100139684.
Adenoid cystic carcinoma of the parotid gland often recurs locally, or metastases develop, after initial treatment with surgery and radiotherapy. We report a patient with an inoperable local recurrence of previously irradiated adenoid cystic carcinoma, who was treated with tamoxifen, an oestrogen receptor antagonist. After 18 months of treatment with tamoxifen, MRI showed a partial response, and further clinical progression of the disease was halted.
腮腺腺样囊性癌在初次接受手术和放疗后常出现局部复发或发生转移。我们报告了1例既往接受过放疗的腺样囊性癌局部复发且无法手术的患者，该患者接受了雌激素受体拮抗剂他莫昔芬治疗。接受他莫昔芬治疗18个月后，磁共振成像（MRI）显示部分缓解，疾病进一步的临床进展得以停止。
