Agabiti-Rosei E, Muiesan M L
Cattedra Semeiotica e Metodologia Medica, Università di Brescia, Italy. agabiti@master cci.unibs.it
Curr Opin Nephrol Hypertens. 1998 Mar;7(2):211-6. doi: 10.1097/00041552-199803000-00011.
In the general population and in patients with essential hypertension the presence of left ventricular hypertrophy is a powerful predictor of cardiovascular events, independent of blood pressure and other cardiovascular risk factors. The prevalence of left ventricular hypertrophy increases with age and with the severity of renal impairment. Left ventricular hypertrophy is also a sensitive indicator of vascular structural changes in both large and small arteries. The possibility of reversing left ventricular hypertrophy therefore represents a major therapeutic goal for the treatment of hypertensive patients. Several studies examining the characteristics of left ventricular hypertrophy in the elderly, the interrelations between cardiac and vascular hypertrophy, the possibility of reversing left ventricular hypertrophy and its consequent prognostic value will be reported and commented on in the present review.
在普通人群和原发性高血压患者中，左心室肥厚的存在是心血管事件的有力预测指标，独立于血压和其他心血管危险因素。左心室肥厚的患病率随年龄增长和肾功能损害的严重程度而增加。左心室肥厚也是大、小动脉血管结构变化的敏感指标。因此，逆转左心室肥厚的可能性是高血压患者治疗的主要目标。本综述将报告并评论几项研究，这些研究探讨了老年人左心室肥厚的特征、心脏和血管肥厚之间的相互关系、逆转左心室肥厚的可能性及其后续的预后价值。
