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异前列腺素的命名法:一项提议。

Nomenclature of isoprostanes: a proposal.

作者信息

Rokach J, Khanapure S P, Hwang S W, Adiyaman M, Lawson J A, FitzGerald G A

机构信息

Claude Pepper Institute, Florida Institute of Technology, Melbourne 32901-6975, USA.

出版信息

Prostaglandins. 1997 Dec;54(6):853-73. doi: 10.1016/s0090-6980(97)00184-6.

DOI:10.1016/s0090-6980(97)00184-6
PMID:9533181
Abstract

We have proposed a nomenclature system for the isoprostanes, a new class of natural products formed in vivo by the free-radical peroxidation of polyunsaturated fatty acids. Our proposed nomenclature is based on the assignment of four isoprostanes, 1, 9, 17, and 25, as representatives of the four classes of isoprostanes derived from arachidonic acid (AA). We have attempted as much as possible to retain elements from the familiar prostaglandin nomenclature. In this proposal, we have used the abbreviation i.p. for isoprostane. We have classified isoprostane classes or types based on omega-carbon as being the starting reference. Roman numerals I-VI refer the six types of isoprostanes derived from eicosapentaenoic acid (EPA) and III-VI refer to the four types derived from AA. This nomenclature can be applied to isoprostanes derived from other PUFAs also.

摘要

我们已经提出了一种异前列腺素的命名系统,异前列腺素是一类新的天然产物,由多不饱和脂肪酸在体内通过自由基过氧化作用形成。我们提出的命名基于将四种异前列腺素(1、9、17和25)指定为源自花生四烯酸(AA)的四类异前列腺素的代表。我们已尽可能保留熟悉的前列腺素命名中的元素。在本提议中,我们使用缩写i.p.表示异前列腺素。我们根据ω-碳作为起始参考对异前列腺素类别或类型进行了分类。罗马数字I-VI指源自二十碳五烯酸(EPA)的六种异前列腺素类型,III-VI指源自AA的四种类型。这种命名也可应用于源自其他多不饱和脂肪酸的异前列腺素。

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Nomenclature of isoprostanes: a proposal.异前列腺素的命名法:一项提议。
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2
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