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基于假设检验解读法医DNA证据。

Interpreting forensic DNA evidence on the basis of hypotheses testing.

作者信息

Fukshansky N, Bär W

机构信息

Institut für Rechtsmedizin Universität Zürich-Irchel, Switzerland.

出版信息

Int J Legal Med. 1998;111(2):62-6. doi: 10.1007/s004140050116.

DOI:10.1007/s004140050116
PMID:9541852
Abstract

Analysis of a mixed biological stain by means of highly polymorphic VNTR systems usually reveals a profile composed of multiple markers. If the victim and one or several suspects match the profile the evidential strength of the matches has to be very carefully analysed. It is shown that a treatment to evaluate mixed stains within the scope of a hypotheses testing approach yields a formula identical to one proposed recently by Weir und coauthors. A simple combinatorial proof of this formula is presented. Further, a special computational formula is derived for the cases where the formula of Weir turns out to be cumbersome.

摘要

通过高度多态的可变数目串联重复序列(VNTR)系统对混合生物污渍进行分析,通常会揭示出由多个标记组成的图谱。如果受害者与一名或多名嫌疑人的图谱匹配,则必须非常仔细地分析这些匹配的证据强度。结果表明,在假设检验方法的范围内对混合污渍进行评估的一种处理方法会产生一个与Weir及其合著者最近提出的公式相同的公式。给出了该公式的一个简单组合证明。此外,针对Weir公式变得繁琐的情况,推导了一个特殊的计算公式。

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