Wu J
Department of Physics, University of Vermont, Burlington 05405, USA.
Ultrasound Med Biol. 1998 Feb;24(2):267-74. doi: 10.1016/s0301-5629(97)00246-9.
Temperature elevation vs. time generated by a focused Gausssian ultrasound beam in the presence of contrast agents has been calculated using a perfect absorbing disc model. The results suggest that, if the contrast agent (Albunex) is introduced into the body intravenously, the temperature rise in the heart, which is 4.5 cm from the transducer, generated by 110-mW (the corresponding acoustic intensity at the transducer front surface is 0.4 W/cm2) 2-MHz ultrasound is about 2 degrees C in 10 s. The relationship between temperature rise and the blood perfusion, acoustic power and focal length is discussed.
利用理想吸收圆盘模型计算了聚焦高斯超声束在存在造影剂的情况下温度随时间的升高情况。结果表明，如果将造影剂（白蛋白微球）静脉注入体内，由110毫瓦（换能器前表面相应的声强为0.4瓦/平方厘米）的2兆赫超声在距换能器4.5厘米处的心脏中产生的温度升高在10秒内约为2摄氏度。讨论了温度升高与血液灌注、声功率和焦距之间的关系。
