Zatonski W A, McMichael A J, Powles J W
Department of Epidemiology and Cancer Prevention, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.
BMJ. 1998 Apr 4;316(7137):1047-51. doi: 10.1136/bmj.316.7137.1047.
To investigate the reasons for the decline in deaths attributed to ischaemic heart disease in Poland since 1991 after two decades of rising rates.
Recent changes in mortality were measured as percentage deviations in 1994 from rates predicted by extrapolation of sex and age specific death rates for 1980-91 for diseases of the circulatory system and selected other categories. Available data on national and household food availability, alcohol consumption, cigarette smoking, socioeconomic indices, and medical services over time were reviewed.
Age specific and age standardised rates of death attributed to ischaemic heart disease and related causes.
The change in trend in mortality attributed to diseases of the circulatory system was similar in men and women and most marked (> 20%) in early middle age. For ages 45 to 64 the decrease was greatest for deaths attributed to ischaemic heart disease and atherosclerosis (around 25%) and less for stroke (< 10%). For most of the potentially explanatory variables considered, there were no corresponding changes in trend. However, between 1986-90 and 1994 there was a marked switch from animal fats (estimated availability down 23%) to vegetable fats (up 48%) and increased imports of fruit.
Reporting biases are unlikely to have exaggerated the true fall in ischaemic heart disease; neither is it likely to be mainly due to changes in smoking, drinking, stress, or medical care. Changes in type of dietary fat and increased supplies of fresh fruit and vegetables seem to be the best candidates.
调查自1991年起波兰缺血性心脏病死亡率在经历了二十年的上升后开始下降的原因。
以1994年死亡率相对于根据1980 - 1991年循环系统疾病及其他选定类别疾病的性别和年龄别死亡率外推预测值的百分比偏差来衡量近期死亡率的变化。回顾了随时间推移可获得的关于国家和家庭食物供应、酒精消费、吸烟、社会经济指数及医疗服务的数据。
缺血性心脏病及相关病因的年龄别和年龄标准化死亡率。
循环系统疾病死亡率的趋势变化在男性和女性中相似,且在中年早期最为显著(>20%)。对于45至64岁人群,缺血性心脏病和动脉粥样硬化导致的死亡下降幅度最大(约25%),中风导致的死亡下降幅度较小(<10%)。对于所考虑的大多数潜在解释变量,趋势没有相应变化。然而,在1986 - 1990年至1994年期间,出现了从动物脂肪(估计供应量下降23%)到植物脂肪(上升48%)的显著转变,且水果进口增加。
报告偏差不太可能夸大缺血性心脏病死亡率的实际下降;其下降也不太可能主要归因于吸烟、饮酒、压力或医疗护理的变化。膳食脂肪类型的改变以及新鲜水果和蔬菜供应的增加似乎是最有可能的原因。