沙雷菌素A - C：源自沙雷曲霉菌核的新型细胞毒性真菌代谢产物。
Arenarins A-C: new cytotoxic fungal metabolites from the sclerotia of aspergillus arenarius.
作者信息
Oh H, Gloer JB, Wicklow DT, Dowd PF
机构信息
Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois 61604, USA.
出版信息
J Nat Prod. 1998 May;61(5):702-5. doi: 10.1021/np980001t.
Three new terphenyl-type metabolites, arenarins A-C (1-3), have been isolated from the sclerotia of Aspergillus arenarius (NRRL 5012). The structures of these compounds were elucidated by analysis of 1-D and 2-D NMR data. Arenarins A-C exhibited mild activity in feeding assays against the dried-fruit beetle Carpophilus hemipterus and cytotoxicity against human tumor cell lines.
从沙曲霉（NRRL 5012）的菌核中分离出了三种新的三联苯型代谢产物，沙曲菌素A - C（1 - 3）。通过一维和二维核磁共振数据的分析阐明了这些化合物的结构。沙曲菌素A - C在针对干果甲虫半翅目锯谷盗的摄食试验中表现出轻微活性，并对人类肿瘤细胞系具有细胞毒性。
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