Yaguchi H, Ishigooka M, Hayami S, Kobayashi T, Kubota Y, Nakada T, Mitobe K
Department of Urology, Yamagata University School of Medicine, Japan.
Int Urol Nephrol. 1998;30(2):107-12. doi: 10.1007/BF02550562.
In order to investigate the effect of triathlon and renal function of normal subjects, we evaluated the excretion of urinary enzymes and proteins before and after triathlon. From 6 subjects samples were obtained 24 hours after the first urine collection. We performed quantification of urinary total protein, beta2-microglobulin (beta2-M), N-acetyl-beta-D-glucosaminidase activity (NAG), and concentration of urinary creatinine from each participant. There was a significant increase in urinary total protein excretion immediately after triathlon (p<0.01). The urinary beta2-M and NAG excretions after triathlon were higher than the initial values. Post-exercise proteinuria in one subject persisted until the next morning, whereas the increased excretion of urinary beta2-M and NAG returned to the pre-exercise level at least 24 hours after triathlon. It appears to be reasonable to presume that glomerular damage may persist in some subjects who do heavy exercise.
为了研究铁人三项运动对正常受试者肾功能的影响，我们评估了铁人三项运动前后尿酶和蛋白质的排泄情况。从6名受试者中，在首次收集尿液24小时后采集样本。我们对每位参与者的尿总蛋白、β2-微球蛋白（β2-M）、N-乙酰-β-D-氨基葡萄糖苷酶活性（NAG）以及尿肌酐浓度进行了定量分析。铁人三项运动后立即出现尿总蛋白排泄显著增加（p<0.01）。铁人三项运动后尿β2-M和NAG排泄高于初始值。一名受试者运动后蛋白尿持续到第二天早上，而尿β2-M和NAG排泄增加在铁人三项运动后至少24小时恢复到运动前水平。推测在进行剧烈运动的一些受试者中可能存在肾小球损伤似乎是合理的。
