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铜绿假单胞菌溶原性建立缺陷突变体的特性分析

Characterization of Pseudomonas aeruginosa mutants deficient in the establishment of lysogeny.

作者信息

Miller R V, Ku C M

出版信息

J Bacteriol. 1978 Jun;134(3):875-83. doi: 10.1128/jb.134.3.875-883.1978.

DOI:10.1128/jb.134.3.875-883.1978
PMID:96103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC222334/
Abstract

Mutants of Pseudomonas aeruginosa with impaired ability to establish a lysogenic relationship with temperate bacteriophage (Les-) have been isolated. These les mutations map to two areas of the P. aeruginosa chromosomal map as determined by conjugational and transductional analyses. Two phenotypic classes of Les- mutants were identified. One class of mutations has pleiotropic effects on DNA metabolism. These mutants are unable to recombine genetic material acquired as a result of either conjugation or transduction (Rec-). In addition, the ability of these Les- Rec- mutants to repair UV-induced damage to bacteriophage is reduced (host-cell reactivation deficient, Hcr-). Mutants of the second class are Les-, Rec+, and Hcr+.

摘要

已分离出与温和噬菌体建立溶原关系能力受损的铜绿假单胞菌突变体（Les-）。通过接合和转导分析确定，这些les突变定位于铜绿假单胞菌染色体图谱的两个区域。鉴定出了两类Les-突变体的表型。一类突变对DNA代谢具有多效性影响。这些突变体无法重组因接合或转导而获得的遗传物质（Rec-）。此外，这些Les-Rec-突变体修复紫外线诱导的噬菌体损伤的能力降低（宿主细胞再活化缺陷，Hcr-）。第二类突变体是Les-、Rec+和Hcr+。

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Characterization of Pseudomonas aeruginosa mutants deficient in the establishment of lysogeny.铜绿假单胞菌溶原性建立缺陷突变体的特性分析
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本文引用的文献

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Effects of radiation on transduction on Pseudomonas aeruginosa.辐射对铜绿假单胞菌转导的影响。
Virology. 1962 Sep;18:89-94. doi: 10.1016/0042-6822(62)90180-0.
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A genetic analysis of non-disjunction and mitotic recombination in Neurospora crassa.粗糙脉孢菌中不分离现象和有丝分裂重组的遗传分析。
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A thermosensitive recombination deficient mutant of Pseudomonas aeruginosa.铜绿假单胞菌的一种热敏重组缺陷突变体。
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Investigation of the mating system of Pseudomonas aeruginosa strain 1. II. Mapping of a number of early markers.铜绿假单胞菌菌株1交配系统的研究。II. 一些早期标记的定位。
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Investigation of the mating system of Pseudomonas aeruginosa strain 1. 3. Kinetic studies on the transfer of the sex factor (FP).铜绿假单胞菌菌株1交配系统的研究。3. 性因子（FP）转移的动力学研究。
Genet Res. 1968 Oct;12(2):139-45. doi: 10.1017/s0016672300011757.
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Mutants of Pseudomonas aeruginosa with reduced recombination ability.重组能力降低的铜绿假单胞菌突变体。
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Radiation-sensitive mutants of Pseudomonas aeruginosa with reduced host-cell reactivation of bacteriophages.铜绿假单胞菌的辐射敏感突变体，其噬菌体的宿主细胞再激活能力降低。
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Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants.通过分离和鉴定转移缺陷型突变体，对大肠杆菌中由F因子决定的接合转移进行遗传分析。
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Behavior of lambda bacteriophage in a recombination deficienct strain of Escherichia coli.λ噬菌体在大肠杆菌重组缺陷菌株中的行为
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