棉花植物粉尘的急性吸入毒性
Acute inhalation toxicity of cotton plant dusts.
作者信息
Rylander R, Snella M C
出版信息
Br J Ind Med. 1976 Aug;33(3):175-80. doi: 10.1136/oem.33.3.175.
Abstract
The number of free lung-cells was studied in guinea-pigs after acute exposure to extracts of various cotton dusts. A good correlation was found between the increase in number of leucocytes in the airways and the number of Gram-negative bacteria in the different dusts. Experiments using the Shwartzmann reaction and the Limulus titration test demonstrated a relationship between the content of different endotoxins in the dusts and the pulmonary reaction. A model for the acute exposure effects after exposure to cotton dust is proposed.
摘要
研究了豚鼠急性暴露于各种棉尘提取物后游离肺细胞的数量。发现气道中白细胞数量的增加与不同粉尘中革兰氏阴性菌的数量之间存在良好的相关性。使用施瓦茨曼反应和鲎试剂滴定试验的实验证明了粉尘中不同内毒素的含量与肺部反应之间的关系。提出了一个接触棉尘后急性暴露效应的模型。
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