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从在小鼠中引发脆弱拟杆菌纯感染开始就使用半固体琼脂。

Use of semisolid agar from initiation of pure Bacteroides fragilis infection in mice.

作者信息

Walker C B, Wilkins T D

出版信息

Infect Immun. 1976 Sep;14(3):721-5. doi: 10.1128/iai.14.3.721-725.1976.

Abstract

The development of a pure Bacteroides fragilis infection in mice is described. The infection produces large subcutaneous abscesses at the site of injection which can be observed grossly within 7 days after injection. The infection was initiated by infection of pure cultures grown in semisolid agar medium. Similar infections were also produced with pure cultures of B. distasonis, B. ovatus, B. thetaiotaomicron, and B. vulgatus. However, a distinct deoxyribonucleic acid homology group, formerly classified as B. thetaiotaomicron, did not produce abscesses in any of the mice tested.

摘要

本文描述了小鼠中脆弱拟杆菌纯感染的发展情况。该感染在注射部位产生大的皮下脓肿,在注射后7天内可肉眼观察到。感染由在半固体琼脂培养基中生长的纯培养物感染引发。用解氏拟杆菌、卵形拟杆菌、多形拟杆菌和普通拟杆菌的纯培养物也产生了类似的感染。然而,一个以前被归类为多形拟杆菌的独特脱氧核糖核酸同源组在任何测试小鼠中都未产生脓肿。

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