脆弱拟杆菌亚种的抗生素敏感性
Antibiotic susceptibility of the subspecies of Bacteroides fragilis.
作者信息
Blazevic D J
出版信息
Antimicrob Agents Chemother. 1976 Mar;9(3):481-4. doi: 10.1128/AAC.9.3.481.
Abstract
Strains (115) of Bacteroides fragilis were identified at the subspecific level and were tested for susceptibility to ampicillin, cephalothin, chloramphenicol, clindamycin, penicillin, and tetracycline using an agar dilution technique. We tested the following strains: B. fragilis subsp. distasonis, 12; B. fragilis subsp. fragilis, 39; B. fragilis subsp. ovatus, 10; B. fragilis subsp. thetaiotaomicron, 32; B. fragilis subsp. vulgatus, 10; and B. fragilis subsp. "other," 12. There were no marked differences in susceptibility between the subspecies. One strain of B. fragilis subsp. thetaiotaomicron had a minimal inhibitory concentration of 12.5 mug/ml for clindamycin, but all other strains were susceptible. All the strains were susceptible to chloramphenicol. Susceptibility to tetracycline was variable. Only a few strains were susceptible to the penicillins and cephalothin.
摘要
对115株脆弱拟杆菌进行了亚种水平的鉴定，并采用琼脂稀释技术检测了它们对氨苄西林、头孢噻吩、氯霉素、克林霉素、青霉素和四环素的敏感性。我们检测了以下菌株：解脲拟杆菌亚种12株；脆弱拟杆菌亚种39株；卵形拟杆菌亚种10株；多形拟杆菌亚种32株；普通拟杆菌亚种10株；以及“其他”脆弱拟杆菌亚种12株。各亚种之间的敏感性没有显著差异。1株多形拟杆菌亚种对克林霉素的最低抑菌浓度为12.5μg/ml，但所有其他菌株均敏感。所有菌株对氯霉素均敏感。对四环素的敏感性各不相同。只有少数菌株对青霉素和头孢噻吩敏感。
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