Zhao Z F, Guo H, Huang X X
Changzhi Medical College, Changzhi, Shanxi Province, People's Republic of China.
Southeast Asian J Trop Med Public Health. 1997;28 Suppl 1:155-7.
Two antigens of Taenia solium cysticercus, cystic fluid antigen (CFA) and the culture medium antigen (CMA), were used respectively to immunize rabbits in order to obtain immunosera. The CMA immunoserum added to culture medium with cysticerci limited the activities of the bladder worms. By using the scanning electronmicroscope, we could observe particulate deposits on the surface of the scolices, suckers and necks of the worms. The CFA immunoserum group showed similar changes but the deposit was less than that on the worms in the former group and appeared mainly on the cystic wall. After adding complement to the two groups mentioned above, we found that the microcilia on the surface of the worms were swollen and were seriously damaged. The worms treated with praziquantel were damaged over large area of their surfaces and were affected deep into their tissues. The damaged parts of the worms were quite different between the two groups. CMA is secreted by the living worms and therefore the serum antibodies are more effective than CFA in anti-parasite activity.
分别用猪带绦虫囊尾蚴的两种抗原，即囊液抗原（CFA）和培养液抗原（CMA）免疫家兔以获得免疫血清。将CMA免疫血清加入含有囊尾蚴的培养液中可限制虫体的活动。通过扫描电子显微镜，我们可以观察到虫体头节、吸盘和颈部表面有颗粒状沉积物。CFA免疫血清组显示出类似的变化，但沉积物比前一组虫体上的少，且主要出现在囊壁上。在上述两组中加入补体后，我们发现虫体表面的微绒毛肿胀且严重受损。用吡喹酮处理的虫体表面大面积受损且组织内部也受到影响。两组虫体的受损部位有很大差异。CMA是活虫分泌的，因此血清抗体在抗寄生虫活性方面比CFA更有效。
