Klein B E, Klein R, Moss S E
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA.
Invest Ophthalmol Vis Sci. 1998 Jul;39(8):1507-10.
To evaluate the relationships of lens thickness to age, to the presence of a nuclear, cortical, or posterior subcapsular cataract, and to other personal characteristics in participants in the Beaver Dam Eye Study.
Slit lamp photographs taken during a population-based prevalence study were measured for lens thickness. In addition, slit lamp photographs were graded for nuclear cataracts, and retroillumination photographs were graded for cortical and posterior subcapsular cataracts. A questionnaire was administered, and height, weight, and blood pressure were measured by protocol.
Lens thickness increased systematically with age in men and women. In multivariate analysis, age, sex (male), cortical cataract, diabetes, nuclear cataract, and former cigarette smoking were related significantly to lens thickness.
Age was the most significant personal characteristic associated with lens thickness among those subjects considered. In addition, other characteristics, including specific cataract types and risk factors for cataracts, also were associated with thickness. Whether lens thickness among people of the same age is associated prospectively with these characteristics requires a longitudinal follow-up.
评估比弗迪姆眼研究参与者中晶状体厚度与年龄、核性、皮质性或后囊下白内障的存在以及其他个人特征之间的关系。
在一项基于人群的患病率研究中拍摄的裂隙灯照片用于测量晶状体厚度。此外，裂隙灯照片用于核性白内障分级，后照法照片用于皮质性和后囊下白内障分级。进行问卷调查，并按照方案测量身高、体重和血压。
男性和女性的晶状体厚度均随年龄系统性增加。在多变量分析中，年龄、性别（男性）、皮质性白内障、糖尿病、核性白内障和既往吸烟与晶状体厚度显著相关。
在所考虑的这些受试者中，年龄是与晶状体厚度相关的最显著个人特征。此外，其他特征，包括特定的白内障类型和白内障危险因素，也与厚度相关。同年龄人群的晶状体厚度是否与这些特征存在前瞻性关联需要进行纵向随访。
