Neuberger J, Adams D, MacMaster P, Maidment A, Speed M
Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2TH.
BMJ. 1998 Jul 18;317(7152):172-5. doi: 10.1136/bmj.317.7152.172.
To compare the priorities of the general public, family doctors, and gastroenterologists in allocating donor livers to potential recipients of liver allograft.
Representative quota sampling of 1000 members of the general public and 200 family doctors, and a postal questionnaire of 100 gastroenterologists.
Respondents were given eight hypothetical case histories (based on real patients) and asked to select recipients for four donor livers. Cases were selected to identify controversial areas such as extremes of age, misuse of alcohol, and intravenous drugs. Respondents were also asked to select the least deserving case and which of seven possible factors (time on waiting list, outcome, age, value to society, return to work, previous use of illicit drugs, and involvement of alcohol in the liver damage) should be used to select patients already listed for transplantation. Focus groups were also held to explore further the reasons for the choices given.
There were considerable differences between the three groups in the choice of the recipients, although alcohol use and antisocial behaviour always rated low. For selection of recipients the general public thought that, in decreasing order of importance, age, outcome, and time on the waiting list were the most important factors in selecting recipients; family doctors rated outcome, age, and likely work status after transplantation and the gastroenterologists outcome, work status, and non-involvement of alcohol in the cause of the liver disease as the most important factors.
The views of the public are at variance with those of clinicians. Further debate is required to ensure an equitable and appropriate distribution of a scarce resource.
比较普通公众、家庭医生和胃肠病学家在为肝移植潜在受者分配供肝时的优先次序。
对1000名普通公众和200名家庭医生进行代表性配额抽样,并对100名胃肠病学家进行邮寄问卷调查。
向受访者提供八个基于真实患者的假设病例史,并要求他们为四个供肝选择受者。选择这些病例是为了确定有争议的领域,如年龄极端情况、酒精滥用和静脉注射药物使用情况。还要求受访者选择最不值得的病例,以及在七个可能的因素(等待名单上的时间、预后、年龄、对社会的价值、重返工作岗位、以前使用非法药物以及酒精在肝损伤中的作用)中,应使用哪个因素来选择已列入移植名单的患者。还举行了焦点小组讨论,以进一步探讨做出这些选择的原因。
尽管饮酒和反社会行为的评分一直较低,但三组在受者选择上存在相当大的差异。在选择受者时,普通公众认为按重要性递减顺序,年龄、预后和等待名单上的时间是选择受者最重要的因素;家庭医生将预后、年龄以及移植后可能的工作状态列为最重要的因素,而胃肠病学家则将预后、工作状态以及酒精未参与肝脏疾病病因列为最重要的因素。
公众的观点与临床医生的观点存在差异。需要进一步辩论,以确保稀缺资源的公平和适当分配。