Nosir Y F, Lequin M H, Kasprzak J D, van Domburg R T, Vletter W B, Yao J, Stoker J, Ten Cate F J, Roelandt J R
Heart Center and Thoraxcenter, Division of Cardiology, University Hospital Rotterdam-Dijkzigt, Erasmus University, Rotterdam, The Netherlands.
Am J Cardiol. 1998 Jul 15;82(2):209-14. doi: 10.1016/s0002-9149(98)00306-3.
The aim of this study was to assess day-to-day variability of left ventricular (LV) volume and ejection fraction (EF) calculated from 3-dimensional echocardiography (3-DE) and to compare the reproducibility of the measurement with magnetic resonance imaging. Forty-six subjects were examined including 15 normal volunteers (group A) and 31 patients with LV dysfunction (group B). Precordial 3-DE acquisition was performed at 2 degrees rotational intervals and repeated 1 week later. Magnetic resonance imaging was performed at 0.5 T. End-diastolic and end-systolic LV volumes were derived using Simpson's rule by manual endocardial tracing of 8 equidistant parallel LV short-axis slices with 3-DE, whereas 9-mm slices were used with magnetic resonance imaging. The mean +/- SD of end-diastolic and end-systolic LV volumes (ml) and EF (%) from magnetic resonance imaging were 182 +/- 75, 121 +/- 76, and 39 +/- 18, whereas those from 3-DE were 182 +/- 76, 121 +/- 77, and 39 +/- 18 respectively. Day-to-day measurements of end-diastolic and end-systolic LV volumes, and EF on 3-DE were not significantly different as assessed with SEE (2.7, 1.1, and 2.4, respectively). Intra- and interobserver SEE for calculating end-diastolic and end-systolic LV volumes and EF for magnetic resonance imaging were 6.3, 4.7, and 2.1 and 13.6, 11.5, and 4.7, respectively, whereas those for 3-DE were 3.1, 4.4, and 2.2 and 6.2, 3.8, and 3.6, respectively. Day-to-day variability of LV volume and EF calculation on 3-DE were small and not significantly different for normal and dysfunctional left ventricles. Observer variabilities of 3-DE were fewer than those of magnetic resonance imaging. Therefore, 3-DE is recommended for serial assessment of LV volume and EF in normal and abnormally shaped ventricles.
本研究的目的是评估通过三维超声心动图（3-DE）计算的左心室（LV）容积和射血分数（EF）的每日变异性，并比较该测量方法与磁共振成像的可重复性。对46名受试者进行了检查，包括15名正常志愿者（A组）和31名左心室功能不全患者（B组）。以2度旋转间隔进行心前区3-DE采集，并在1周后重复进行。在0.5 T下进行磁共振成像。舒张末期和收缩末期LV容积通过Simpson法则，利用3-DE对8个等距平行LV短轴切片进行手动心内膜描记得出，而磁共振成像则使用9毫米切片。磁共振成像得出的舒张末期和收缩末期LV容积（ml）和EF（%）的平均值±标准差分别为182±75、121±76和39±18，而3-DE得出的分别为182±76、121±77和39±18。用SEE评估（分别为2.7、1.1和2.4），3-DE对舒张末期和收缩末期LV容积以及EF的每日测量值无显著差异。磁共振成像计算舒张末期和收缩末期LV容积以及EF的观察者内和观察者间SEE分别为6.3、4.7和2.1以及13.6、11.5和4.7，而3-DE的分别为3.1、4.4和2.2以及6.2、3.8和3.6。3-DE计算LV容积和EF的每日变异性较小，正常和功能不全左心室之间无显著差异。3-DE的观察者变异性低于磁共振成像。因此，推荐使用3-DE对正常和形状异常的心室进行LV容积和EF的系列评估。
