CrFK猫肾细胞产生一种类似RD114的内源性病毒，该病毒可包装基于鼠白血病病毒的载体。
CrFK feline kidney cells produce an RD114-like endogenous virus that can package murine leukemia virus-based vectors.
作者信息
Baumann J G, Günzburg W H, Salmons B
机构信息
Institute of Virology, University of Veterinary Sciences, A-1210 Vienna, Austria.
出版信息
J Virol. 1998 Sep;72(9):7685-7. doi: 10.1128/JVI.72.9.7685-7687.1998.
Abstract
The feline kidney cell line CrFK is used extensively for viral infectivity assays and for study of the biology of various retroviruses and derived vectors. We demonstrate the production of an endogenous, RD114-like, infectious retrovirus from CrFK cells. This virus also is shown to efficiently package Moloney murine leukemia virus vectors.
摘要
猫肾细胞系CrFK被广泛用于病毒感染性测定以及各种逆转录病毒及其衍生载体的生物学研究。我们证明了CrFK细胞能产生一种内源性的、类似RD114的传染性逆转录病毒。这种病毒还被证明能有效地包装莫洛尼鼠白血病病毒载体。
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