Atiq M, Suria A, Nizami S Q, Ahmed I
Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan.
Acta Paediatr. 1998 Jul;87(7):737-40. doi: 10.1080/080352598750013806.
This study was conducted to evaluate the vitamin D status of healthy breastfed Pakistani infants and their nursing mothers. Sixty-two breastfed healthy infants and their nursing mothers belonging to the upper and lower socioeconomic classes were examined. Serum 25-hydroxy vitamin D [25(OH)D], serum calcium, phosphorus and alkaline phosphatase were measured. The mean serum 25(OH)D in infants was 34.59 +/- 26.56 nmol/l. Fifty-five percent of infants and 45% of mothers had very low serum 25(OH)D levels (<25 nmol/l). Significantly higher levels were found in infants of lower socioeconomic class (p < 0.001) and in those living in mud houses (p = 0.002) and infants >6 months (p < 0.001). A high prevalence of vitamin D deficiency was found in breastfed infants and nursing mothers, predominantly among those belonging to the upper socioeconomic class. Infants of the lower socioeconomic class had comparatively higher serum 25(OH)D levels, but even these levels were below the normal range for infants (90 +/- 27.5 nmol/l).
本研究旨在评估健康的巴基斯坦母乳喂养婴儿及其哺乳母亲的维生素D状况。对62名来自社会经济阶层上下层的母乳喂养健康婴儿及其哺乳母亲进行了检查。测量了血清25-羟维生素D [25(OH)D]、血清钙、磷和碱性磷酸酶。婴儿血清25(OH)D的平均值为34.59±26.56 nmol/l。55%的婴儿和45%的母亲血清25(OH)D水平极低(<25 nmol/l)。社会经济阶层较低的婴儿(p < 0.001)、居住在泥屋中的婴儿(p = 0.002)以及6个月以上的婴儿(p < 0.001)中，血清25(OH)D水平显著更高。母乳喂养婴儿和哺乳母亲中维生素D缺乏的患病率很高，主要集中在社会经济阶层上层的人群中。社会经济阶层较低的婴儿血清25(OH)D水平相对较高，但即便如此，这些水平仍低于婴儿的正常范围(90±27.5 nmol/l)。
