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西德婴儿白血病的发病趋势与切尔诺贝利事故导致的宫内暴露的关系。

Trends in infant leukaemia in West Germany in relation to in utero exposure due to Chernobyl accident.

作者信息

Steiner M, Burkart W, Grosche B, Kaletsch U, Michaelis J

机构信息

Institut für Strahlenhygiene, Bundesamt für Strahlenschutz, Oberschleissheim, Germany.

出版信息

Radiat Environ Biophys. 1998 Jul;37(2):87-93. doi: 10.1007/s004110050099.

Abstract

A temporary increase in the incidence of infant leukaemia in Greece was reported by Petridou et al., which was attributed to in utero exposure to ionising radiation resulting from the Chernobyl accident. We performed a similar analysis based on the data of the German Childhood Cancer Registry in order to check whether the observation could be confirmed by means of independent data. Applying the same definitions as Petridou et al., we also observed an increased incidence of infant leukaemia in a cohort of children born after the Chernobyl accident. More detailed analyses, regarding areas with different contamination levels and dose rate gradients over time after the accident, showed, however, no clear trend with regard to exposure. It would therefore appear less likely that the observed effect was caused by exposure to ionising radiation due to the Chernobyl accident.

摘要

佩特里杜等人报告称,希腊婴儿白血病发病率出现了短暂上升,这归因于子宫内暴露于切尔诺贝利事故产生的电离辐射。我们基于德国儿童癌症登记处的数据进行了类似分析,以检查这一观察结果能否通过独立数据得到证实。采用与佩特里杜等人相同的定义,我们在切尔诺贝利事故后出生的一组儿童中也观察到婴儿白血病发病率有所上升。然而,针对事故后不同污染水平区域以及随时间变化的剂量率梯度进行的更详细分析显示,在暴露方面没有明显趋势。因此,观察到的效应由切尔诺贝利事故导致的电离辐射暴露引起的可能性似乎较小。

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