Franco L H, Joffé E B, Puricelli L, Tatian M, Seldes A M, Palermo J A
Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón II, Ciudad Universitaria, (1428) Buenos Aires, Argentina.
J Nat Prod. 1998 Sep;61(9):1130-2. doi: 10.1021/np970493u.
Five new indole alkaloids, meridianins A-E (1-5), have been isolated from the tunicate Aplidium meridianum, which was collected at a depth of 100 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Compounds 2-5 showed cytotoxicity toward murine tumor cell lines.
从南乔治亚群岛附近100米深处采集的被囊动物子午海鞘中分离出了5种新的吲哚生物碱，即子午海鞘素A-E（1-5），并通过光谱技术阐明了它们的结构。化合物2-5对鼠类肿瘤细胞系显示出细胞毒性。
