Farrag A, Farwiz H M, Khedr E H, Mahfouz R M, Omran S M
Department of Neuropsychiatry, Assiut University, Assiut, Egypt.
Dement Geriatr Cogn Disord. 1998 Nov-Dec;9(6):323-8. doi: 10.1159/000017084.
The aim of this study was to determine the prevalence rate of Alzheimer's disease (AD) and other types of dementias among the population over the age of 60 years in Assiut governorate. A 3-phase cross-sectional population-based study was carried out to screen 2, 000 subjects residing in 11 different locations representing the sociocultural status of the area. We subjected each proband to a modified form of the Mini Mental State Examination test. Subjects scored 21 or less were investigated according to a standardized protocol. We found 90 demented subjects yielding a crude prevalence ratio (case per 100 population over the age of 60) of 4.5. A diagnosis of subtypes of dementia was reached in 83 cases. Prevalence ratios for dementia subtypes were 2.2 for AD, 0.95 for multi-infarct dementia. 0.55 for mixed dementias and 0.45 for secondary dementias. Age-specific prevalence tends to be doubled every 5 years. Occupation, level of education and residence did not affect the prevalence or severity of dementia. Comparison with other studies suggests that dementia of all types is as frequent in Assiut governorate as elsewhere.
本研究旨在确定阿斯尤特省60岁以上人群中阿尔茨海默病（AD）及其他类型痴呆症的患病率。开展了一项基于人群的三阶段横断面研究，以筛查居住在代表该地区社会文化状况的11个不同地点的2000名受试者。我们让每位先证者接受改良版简易精神状态检查表测试。得分21分及以下的受试者按照标准化方案进行调查。我们发现90名痴呆受试者，粗患病率（每100名60岁以上人群中的病例数）为4.5。83例患者确诊为痴呆症亚型。痴呆症亚型的患病率分别为：AD为2.2，多发梗死性痴呆为0.95，混合性痴呆为0.55，继发性痴呆为0.45。特定年龄的患病率每5年往往会翻倍。职业、教育程度和居住地点并未影响痴呆症的患病率或严重程度。与其他研究相比表明，阿斯尤特省各类痴呆症的发病率与其他地方一样高。
