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使用Amplicor和Ultra Direct检测法测定血浆中1型人类免疫缺陷病毒RNA水平的策略成本比较。

Comparison of costs of strategies for measuring levels of human immunodeficiency virus type 1 RNA in plasma by using Amplicor and Ultra Direct assays.

作者信息

Raboud J M, Seminari E, Rae S L, Harrigan P R, Hogg R S, Conway B, Sherlock C, Schechter M T, O'Shaughnessy M V, Montaner J S

机构信息

Canadian HIV Trials Network, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

J Clin Microbiol. 1998 Nov;36(11):3369-71. doi: 10.1128/JCM.36.11.3369-3371.1998.

DOI:10.1128/JCM.36.11.3369-3371.1998
PMID:9774597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105333/
Abstract

The costs of four algorithms for monitoring plasma human immunodeficiency virus type 1 RNA were compared. For patients with strong virologic responses, the use of Ultra Direct exclusively was the cheapest strategy. For patients with weak virologic responses, small savings could be obtained by using Amplicor and retesting only samples with values below 500 copies/ml with Ultra Direct.

摘要

对监测血浆1型人类免疫缺陷病毒RNA的四种算法的成本进行了比较。对于病毒学反应强烈的患者，仅使用Ultra Direct是最便宜的策略。对于病毒学反应较弱的患者，通过使用Amplicor并仅对Ultra Direct检测值低于500拷贝/毫升的样本进行重新检测，可节省少量费用。