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角膜曲率计和计算机化视频角膜地形图的临床评估:正常角膜和散光角膜的观察者内及观察者间变异性

Clinical evaluation of keratometry and computerised videokeratography: intraobserver and interobserver variability on normal and astigmatic corneas.

作者信息

Karabatsas C H, Cook S D, Papaefthymiou J, Turner P, Sparrow J M

机构信息

Department of Ophthalmology, Bristol Eye Hospital.

出版信息

Br J Ophthalmol. 1998 Jun;82(6):637-42. doi: 10.1136/bjo.82.6.637.

Abstract

AIMS

To evaluate intra- and interobserver variability in measurements on normal and astigmatic corneas with keratometry and computerized videokeratography.

METHODS

Keratometric readings with the 10 SL/O Zeiss keratometer and topographic maps with the TMS-1 were obtained by two independent examiners on 32 normal and 33 postkeratoplasty corneas. Inter- and intraobserver coefficients of variability (COR) for measurements of steep and flat meridian power and location, in addition to the magnitude of astigmatism, were assessed.

RESULTS

Compared with TMS-1, the 10 SL/O keratometer showed a superior repeatability in measuring normal corneas (intraobserver COR for keratometry and TMS-1 respectively: 0.22 and 0.30 D for steep meridian power; 0.18 and 0.44 D for flat meridian power; 0.26 and 0.40 D for astigmatism; 5 degrees and 26 degrees for steep meridian location; 5 degrees and 13 degrees for flat meridian location). Astigmatism intraobserver COR (0.20 D and 0.26 D for the two observers) and interobserver COR (0.28 D) of the keratometer for normal corneas was very good and not affected by observers' experience. Repeatability of the TMS-1 on normal corneas was found to be: (a) observer related, and (b) astigmatism related. A novice observer showed a much greater COR (1.62 D for astigmatism, 30 degrees for flat meridian location) compared with the experienced examiner (0.40 D for astigmatism, 13 degrees for flat meridian location). Higher deviation scores were observed for corneas with higher astigmatism. For the postkeratoplasty corneas, again the keratometer achieved superior reproducibility (astigmatism interobserver COR 1.12 D for keratometry, 4.06 D for TMS-1; steep meridian location interobserver COR 10 degrees for keratometry, 34 degrees for TMS-1).

CONCLUSION

Keratometric readings are more reproducible than topographic data both for normal and postkeratoplasty corneas. The two instruments should not be used interchangeably especially on highly astigmatic corneas. For the TMS-1, users with the same level of experience should be employed in clinical or experimental studies.

摘要

目的

使用角膜曲率计和计算机化视频角膜地形图仪评估正常角膜和散光角膜测量中观察者内和观察者间的变异性。

方法

两名独立检查者使用10 SL/O蔡司角膜曲率计获取角膜曲率读数,并使用TMS-1获取地形图,测量对象为32只正常角膜和33只角膜移植术后的角膜。评估观察者内和观察者间陡度和扁平子午线屈光力、位置测量以及散光度数的变异系数(COR)。

结果

与TMS-1相比,10 SL/O角膜曲率计在测量正常角膜时显示出更高的重复性(角膜曲率计和TMS-1观察者内COR分别为:陡度子午线屈光力0.22 D和0.30 D;扁平子午线屈光力0.18 D和0.44 D;散光0.26 D和0.40 D;陡度子午线位置5度和26度;扁平子午线位置5度和13度)。角膜曲率计对正常角膜的观察者内散光COR(两名观察者分别为0.20 D和0.26 D)和观察者间COR(0.28 D)非常好,且不受观察者经验影响。发现TMS-1在正常角膜上的重复性为:(a)与观察者相关,(b)与散光相关。与经验丰富的检查者(散光0.40 D,扁平子午线位置13度)相比,新手观察者的COR要高得多(散光1.62 D,扁平子午线位置30度)。散光度数越高的角膜观察到的偏差分数越高。对于角膜移植术后的角膜,角膜曲率计同样具有更高的再现性(观察者间散光COR:角膜曲率计为1.12 D,TMS-1为4.06 D;观察者间陡度子午线位置COR:角膜曲率计为10度,TMS-1为34度)。

结论

对于正常角膜和角膜移植术后的角膜,角膜曲率计读数比地形图数据更具可重复性。这两种仪器不应互换使用,尤其是在高度散光角膜上。对于TMS-1,临床或实验研究应使用经验水平相同的使用者。

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