Persson L G, Lindström K, Lingfors H, Bengtsson C, Lissner L
Health Centre of Habo, Sweden.
J Epidemiol Community Health. 1998 Jul;52(7):425-32. doi: 10.1136/jech.52.7.425.
To study differences in cardiovascular lifestyle risk factors and biological risk markers in early adult life, with special attention to age and sex differences. Lifestyle cardiovascular risk factors included dietary habits, physical inactivity, smoking, alcohol habits, psychosocial strain, and mental stress. Biological risk markers included anthropometric variables, arterial blood pressure, and serum cholesterol concentration.
A combined individual and community based preventive programme, including health examinations.
All communities in the County of Skaraborg in south western Sweden.
Altogether 12,982 men and women aged 30 or 35 years who underwent health examinations over seven years.
In both sexes, biological risk markers studied were worse in 35 year old subjects than in 30 year olds. Furthermore, a larger proportion of men aged 35 years were smokers and were physically inactive compared with 30 year old men. However, dietary habits were better in both sexes in the upper age group. At both ages there were also significant differences between men and women. Women, compared with men, had better dietary habits and lower alcohol consumption but smoked more and experienced greater mental stress and psychosocial strain. All biological risk markers were worse in men than in women at both ages studied. During the observation period, some improvement of the health profile of the participants was observed, indicating a beneficial effect of the intervention programme.
The results indicate that the risk of cardiovascular disease, as assessed from studying lifestyle and biological risk markers, increases early in life, suggesting that preventive measures should start early.
研究成年早期心血管生活方式风险因素和生物学风险标志物的差异,特别关注年龄和性别差异。生活方式心血管风险因素包括饮食习惯、缺乏体育活动、吸烟、饮酒习惯、心理社会压力和精神压力。生物学风险标志物包括人体测量变量、动脉血压和血清胆固醇浓度。
一项基于个体和社区的综合预防计划,包括健康检查。
瑞典西南部斯卡纳堡县的所有社区。
共有12982名年龄在30岁或35岁的男性和女性在7年期间接受了健康检查。
在两个年龄段,35岁受试者的生物学风险标志物均比30岁受试者差。此外,与30岁男性相比,35岁男性中吸烟者和缺乏体育活动者的比例更高。然而,年龄较大组的男女饮食习惯都更好。在两个年龄段,男性和女性之间也存在显著差异。与男性相比,女性饮食习惯更好,饮酒量更低,但吸烟更多,精神压力和心理社会压力更大。在两个研究年龄段,男性的所有生物学风险标志物均比女性差。在观察期内,观察到参与者的健康状况有所改善,表明干预计划具有有益效果。
结果表明,从生活方式和生物学风险标志物研究评估的心血管疾病风险在生命早期就会增加,这表明预防措施应尽早开始。