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肺移植受者的念珠菌吻合口感染:全身和吸入性抗真菌药物联合治疗成功

Candidal anastomotic infection in lung transplant recipients: successful treatment with a combination of systemic and inhaled antifungal agents.

作者信息

Palmer S M, Perfect J R, Howell D N, Lawrence C M, Miralles A P, Davis R D, Tapson V F

机构信息

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

J Heart Lung Transplant. 1998 Oct;17(10):1029-33.

PMID:9811413
Abstract

Anastomotic infection is an uncommon but potentially life-threatening complication after lung transplantation. We recently encountered three lung transplant recipients with invasive candidal anastomotic infection. Two patients were admitted with dyspnea and fever, and one asymptomatic infection was detected on surveillance bronchoscopy. All three patients were treated similarly with a combination of intravenous amphotericin B, inhaled amphotericin B, and oral fluconazole. The combination of systemic and inhaled antifungal agents successfully treated all three cases of anastomotic infection.

摘要

吻合口感染是肺移植术后一种罕见但可能危及生命的并发症。我们最近遇到了3例侵袭性念珠菌吻合口感染的肺移植受者。2例患者因呼吸困难和发热入院,1例无症状感染是在监测支气管镜检查时发现的。所有3例患者均接受了静脉注射两性霉素B、吸入两性霉素B和口服氟康唑联合治疗。全身和吸入抗真菌药物联合成功治疗了所有3例吻合口感染病例。

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Candidal anastomotic infection in lung transplant recipients: successful treatment with a combination of systemic and inhaled antifungal agents.肺移植受者的念珠菌吻合口感染:全身和吸入性抗真菌药物联合治疗成功
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