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输精管结扎术后对精子以外抗原的弱自身抗体反应。

Weak autoantibody reactions to antigens other than sperm after vasectomy.

作者信息

Mathews J D, Skegg D C, Vessey M P, Konice M, Holborow E J, Guillebaud J

出版信息

Br Med J. 1976 Dec 4;2(6048):1359-60. doi: 10.1136/bmj.2.6048.1359.

Abstract

Autoantibody activity against various antigens was measured by indirect immunofluorescence in 97 men about to undergo vasectomy and 170 men who had undergone the operation up to six years earlier. There was a significantly higher prevalence of weakly positive autoantibody reactions among those who had undergone vasectomy. There was, however, no evidence that vasectomy could induce stronger autoantibody reactions such as those associated with autoimmune disease.

摘要

采用间接免疫荧光法,对97名即将接受输精管切除术的男性以及170名在手术完成后六年内接受输精管切除术的男性体内针对各种抗原的自身抗体活性进行了检测。输精管切除术后的男性中,弱阳性自身抗体反应的患病率显著更高。然而,没有证据表明输精管切除术会引发更强的自身抗体反应,例如那些与自身免疫性疾病相关的反应。

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1
Smooth muscle antibody in malignant disease.
Br Med J. 1971 Nov 27;4(5786):511-3. doi: 10.1136/bmj.4.5786.511.
3
Immunologic consequences of vasectomy.
Contraception. 1972 Apr;5(4):269-78. doi: 10.1016/0010-7824(72)90066-2.
4
5
Tissue antibodies in dermatitis herpetiformis and adult coeliac disease.
Lancet. 1971 Apr 24;1(7704):834-6. doi: 10.1016/s0140-6736(71)91499-1.
6
Autoimmune implications of vasectomy in man.
Clin Exp Immunol. 1976 May;24(2):368-9.

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