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白细胞对索状因子(海藻糖-6,6'-二霉菌酸酯)的趋化反应。

Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate).

作者信息

Ofek I, Bekierkunst A

出版信息

J Natl Cancer Inst. 1976 Dec;57(6):1379-81. doi: 10.1093/jnci/57.6.1379.

DOI:10.1093/jnci/57.6.1379
PMID:1003563
Abstract

Cord factor (trehalose-6,6'-dimycolate), a glycolipid extractable from myocobacteria, was chemotactic for peritoneal cells of mice at concentrations from 5 to 25 mug/ml medium, as well as for peripheral white blood cells of mice and humans. At higher concentrations, presumably only macrophages were attracted.

摘要

索状因子(海藻糖-6,6'-二甲酰基海藻糖)是一种可从分枝杆菌中提取的糖脂,在培养基浓度为5至25微克/毫升时,对小鼠腹腔细胞以及小鼠和人类的外周血白细胞具有趋化作用。在较高浓度下,推测仅吸引巨噬细胞。

相似文献

1
Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate).白细胞对索状因子(海藻糖-6,6'-二霉菌酸酯)的趋化反应。
J Natl Cancer Inst. 1976 Dec;57(6):1379-81. doi: 10.1093/jnci/57.6.1379.
2
Participation of tumor necrosis factor in the antitumor activity of mycobacterial trehalose dimycolate (cord factor).肿瘤坏死因子在分枝杆菌海藻糖二霉菌酸酯(索状因子)的抗肿瘤活性中的作用。
Braz J Med Biol Res. 1989;22(3):341-4.
3
Stimulation of thymocyte mitogenic protein secretion and of cytostatic activity of mouse peritoneal macrophages by trehalose dimycolate and muramyldipeptide.海藻糖二霉菌酸酯和胞壁酰二肽对小鼠胸腺细胞促有丝分裂蛋白分泌及小鼠腹腔巨噬细胞细胞抑制活性的刺激作用。
Eur J Immunol. 1980 Aug;10(8):647-53. doi: 10.1002/eji.1830100813.
4
[In vivo and in vitro effect of trehalose dimycolate on tumoricidal activity of peritoneal macrophages from rats].
C R Acad Sci III. 1984;298(7):181-3.
5
Mycolyl glycolipids stimulate macrophages to release a chemotactic factor.霉菌酸糖脂刺激巨噬细胞释放趋化因子。
FEMS Microbiol Lett. 1990 Jan 15;55(1-2):49-53. doi: 10.1016/0378-1097(90)90166-n.
6
Enhancement of nonspecific immunity to bacterial infection by cord factor (6,6'-trehalose dimycolate).海藻糖二霉菌酸酯(索状因子)对细菌感染非特异性免疫力的增强作用。
J Infect Dis. 1977 May;135(5):771-7. doi: 10.1093/infdis/135.5.771.
7
Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice.海藻糖-6,6'-二霉菌酸酯(P3或索状因子)未能增强内毒素对小鼠的致死性。
Infect Immun. 1976 Dec;14(6):1375-7. doi: 10.1128/iai.14.6.1375-1377.1976.
8
Stimulation of macrophages by cord factor and by heat-killed and living BCG.用索状因子以及热灭活和活卡介苗刺激巨噬细胞。
Infect Immun. 1977 Apr;16(1):1-8. doi: 10.1128/iai.16.1.1-8.1977.
9
Biomedical applications of chromatographic fraction containing trehalose dimycolate in squalane emulsion.含有海藻糖二霉菌酸酯的色谱馏分在角鲨烷乳剂中的生物医学应用。
J Chromatogr. 1988 May 25;440:473-8. doi: 10.1016/s0021-9673(00)94552-7.
10
Influence of oil and Tween concentrations on enhanced endotoxin lethality in mice pretreated with emulsified trehalose-6,6'-dimycolate (cord factor).油和吐温浓度对经乳化海藻糖-6,6'-二霉菌酸酯(索状因子)预处理的小鼠内毒素致死性增强的影响。
Infect Immun. 1979 May;24(2):571-2. doi: 10.1128/iai.24.2.571-572.1979.

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Mycobacterial glycolipid cord factor trehalose 6,6'-dimycolate causes a decrease in serum cortisol during the granulomatous response.分枝杆菌糖脂索状因子海藻糖6,6'-二霉菌酸酯在肉芽肿反应期间会导致血清皮质醇水平降低。
Neuroimmunomodulation. 2002;10(5):270-82. doi: 10.1159/000069971.
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Proliferative responses of central and peripheral rat lymphocytes elicited by cord factor (trehalose 6,6'-dimycolate).
由索状因子(海藻糖6,6'-二霉菌酸酯)引发的大鼠中枢和外周淋巴细胞的增殖反应。
Infect Immun. 1981 Jul;33(1):115-9. doi: 10.1128/iai.33.1.115-119.1981.
4
Interstitial and hemorrhagic pneumonitis induced by mycobacterial trehalose dimycolate.分枝杆菌海藻糖二霉菌酸酯诱导的间质性和出血性肺炎。
Am J Pathol. 1982 Mar;106(3):348-55.
5
Granuloma formation and hemopoiesis induced by C36-48-mycolic acid-containing glycolipids from Nocardia rubra.红色诺卡氏菌含C36 - 48分枝菌酸糖脂诱导的肉芽肿形成和造血作用
Infect Immun. 1986 Dec;54(3):869-75. doi: 10.1128/iai.54.3.869-875.1986.
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Stimulation of macrophages by cord factor and by heat-killed and living BCG.用索状因子以及热灭活和活卡介苗刺激巨噬细胞。
Infect Immun. 1977 Apr;16(1):1-8. doi: 10.1128/iai.16.1.1-8.1977.
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Antitumor activity of mycobacterial glycolipid A1.分枝杆菌糖脂A1的抗肿瘤活性。
Infect Immun. 1978 Sep;21(3):914-7. doi: 10.1128/iai.21.3.914-917.1978.