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Infect Immun. 1976 Dec;14(6):1375-7. doi: 10.1128/iai.14.6.1375-1377.1976.
2
Influence of oil and Tween concentrations on enhanced endotoxin lethality in mice pretreated with emulsified trehalose-6,6'-dimycolate (cord factor).油和吐温浓度对经乳化海藻糖-6,6'-二霉菌酸酯（索状因子）预处理的小鼠内毒素致死性增强的影响。
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Participation of tumor necrosis factor in the antitumor activity of mycobacterial trehalose dimycolate (cord factor).肿瘤坏死因子在分枝杆菌海藻糖二霉菌酸酯（索状因子）的抗肿瘤活性中的作用。
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Immunotherapy and vaccination against cancer with non-living BCG and cord factor (trehalose-6,6'-dimycolate).
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引用本文的文献

1
Toxicity of emulsified trehalose-6,6'-dimycolate (cord factor) in mice depends on size distribution of mineral oil droplets.乳化海藻糖-6,6'-二霉菌酸酯（索状因子）对小鼠的毒性取决于矿物油滴的大小分布。
Infect Immun. 1978 Jun;20(3):856-60. doi: 10.1128/iai.20.3.856-860.1978.
2
Influence of oil and Tween concentrations on enhanced endotoxin lethality in mice pretreated with emulsified trehalose-6,6'-dimycolate (cord factor).油和吐温浓度对经乳化海藻糖-6,6'-二霉菌酸酯（索状因子）预处理的小鼠内毒素致死性增强的影响。
Infect Immun. 1979 May;24(2):571-2. doi: 10.1128/iai.24.2.571-572.1979.
3
Regression of a transplanted guinea pig hepatoma after intralesional injection of an emulsified mixture of endotoxin and mycobacterial sulfolipid.在瘤内注射内毒素和分枝杆菌硫脂的乳化混合物后，移植的豚鼠肝癌发生消退。
Infect Immun. 1979 May;24(2):357-62. doi: 10.1128/iai.24.2.357-362.1979.
4
Nonspecific immunostimulant activities of synthetic trehalose-6,6'-diesters (lower homologs of cord factor).合成海藻糖-6,6'-二酯（类脂酸的低级同系物）的非特异性免疫刺激活性。
Infect Immun. 1978 Apr;20(1):12-9. doi: 10.1128/iai.20.1.12-19.1978.

本文引用的文献

1
Hyperreactivity to endotoxin in mice infected with mycobacteria. Induction and elicitation of the reactions.感染分枝杆菌的小鼠对内毒素的高反应性。反应的诱导与激发。
Immunology. 1961 Oct;4(4):354-65.
2
Suppression of urethan-induced lung adenomas in mice treated with trehalose-6,6-dimycolate (cord factor) and living bacillus Calmette Guérin.用海藻糖-6,6-二霉菌酸酯（索状因子）和活卡介苗治疗的小鼠中，对乌拉坦诱导的肺腺瘤的抑制作用
Science. 1971 Dec 17;174(4015):1240-2. doi: 10.1126/science.174.4015.1240.
3
Granuloma formation induced in mice by chemically defined mycobacterial fractions.化学定义的分枝杆菌组分在小鼠中诱导形成肉芽肿。
J Bacteriol. 1969 Oct;100(1):95-102. doi: 10.1128/jb.100.1.95-102.1969.
4
Immune response to sheep red blood cells in mice pretreated with mycobacterial fractions.用分枝杆菌组分预处理的小鼠对绵羊红细胞的免疫反应。
Infect Immun. 1971 Sep;4(3):256-63. doi: 10.1128/iai.4.3.256-263.1971.
5
Cellular reaction in the footpad and draining lymph nodes of mice induced by mycobacterial fractions and BCG bacilli.分枝杆菌组分和卡介苗杆菌诱导的小鼠足垫及引流淋巴结中的细胞反应。
Infect Immun. 1971 Sep;4(3):245-55. doi: 10.1128/iai.4.3.245-255.1971.
6
Granulomatous hypersensitivity to trehalose-6,6'-dimycolate (cord factor) in mice infected with BCG.感染卡介苗的小鼠对海藻糖-6,6'-二霉菌酸酯（索状因子）的肉芽肿性超敏反应。
Infect Immun. 1973 Apr;7(4):631-8. doi: 10.1128/iai.7.4.631-638.1973.
7
Immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets.癌症免疫疗法：在皮内注射附着于油滴的分枝杆菌细胞壁后，已形成的皮内肿瘤出现消退。
J Natl Cancer Inst. 1974 May;52(5):1571-7. doi: 10.1093/jnci/52.5.1571.
8
BCG and cancer (first of two parts).卡介苗与癌症（两部分中的第一部分）
N Engl J Med. 1974 Jun 20;290(25):1413-20. doi: 10.1056/NEJM197406202902506.
9
Suppression of growth of Ehrlich ascites tumor cells in mice by trehalose-6,6'-dimycolate (cord factor) and BCG.海藻糖-6,6'-二甲酰基肌醇（索状因子）和卡介苗对小鼠艾氏腹水瘤细胞生长的抑制作用
Infect Immun. 1974 Jun;9(6):977-84. doi: 10.1128/iai.9.6.977-984.1974.
10
Adjuvant effect of cord factor, a mycobacterial lipid.结核分枝杆菌脂质——索状因子的佐剂效应
Infect Immun. 1976 Mar;13(3):776-81. doi: 10.1128/iai.13.3.776-781.1976.

海藻糖-6,6'-二霉菌酸酯（P3或索状因子）未能增强内毒素对小鼠的致死性。

Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice.

作者信息

Yarkoni E, Meltzer M S, Rapp H J

出版信息

Infect Immun. 1976 Dec;14(6):1375-7. doi: 10.1128/iai.14.6.1375-1377.1976.

DOI:10.1128/iai.14.6.1375-1377.1976
PMID:793994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC415541/
Abstract

The increased endotoxin lethality in mice pretreated with BCG was not observed in mice pretreated with trehalose-6,6'-dimycolate instead of BCG.

摘要

在用海藻糖-6,6'-二霉菌酸酯而非卡介苗预处理的小鼠中，未观察到如用卡介苗预处理的小鼠那样内毒素致死率增加的情况。