Zappacosta B, Persichilli S, De Sole P, Mordente A, Giardina B
Istituto di Chimica e Chimica Clinica, CNR Centro Chimica dei Recettori, Università Cattolica del Sacro Cuore, Rome, Italy.
Arch Oral Biol. 1999 Jun;44(6):485-8. doi: 10.1016/s0003-9969(99)00025-4.
Concentrations of glutathione, uric acid and total antioxidant activity, expressed as Trolox (a water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-smokers and smokers before and just after smoking a single cigarette. There was no statistically significant difference between smokers and non-smokers in uric acid concentrations and total radical-trapping antioxidant capacity, but glutathione concentrations were significantly (p < 0.05) higher in smokers. Smoking of a single cigarette induced a significant reduction in glutathione concentration (p < 0.05). Salivary antioxidant power may affect individual sensitivity toward tobacco stress.
在健康非吸烟者和吸烟者吸一支烟之前及刚吸完后，测量了他们唾液中谷胱甘肽、尿酸的浓度以及以Trolox（一种水溶性维生素E类似物）当量表示的总抗氧化活性。吸烟者和非吸烟者在尿酸浓度和总自由基捕获抗氧化能力方面无统计学显著差异，但吸烟者的谷胱甘肽浓度显著更高（p<0.05）。吸一支烟导致谷胱甘肽浓度显著降低（p<0.05）。唾液抗氧化能力可能会影响个体对烟草应激的敏感性。
