Sargent J D, Dalton M, Demidenko E, Simon P, Klein R Z
Department of Pediatrics, Dartmouth Medical School, Hanover, NH 03756, USA.
Am J Public Health. 1999 Nov;89(11):1690-5. doi: 10.2105/ajph.89.11.1690.
This study examined the effect of an active program of household lead paint hazard abatement, applied over 22 years, on childhood lead poisoning in Massachusetts.
A small areas analysis was used to compare screening blood lead levels of children in Worcester County, Mass (n = 27,590), with those in Providence County, RI (n = 19,071). Data were collapsed according to census tract.
The percentage of children with lead poisoning (blood lead level > or = 20 micrograms/dL [Pe20]) was, on average, 3 times higher in Providence County census tracts (3.2% vs 0.9% in Worcester County census tracts, P < .0001), despite similar percentages of pre-1950s housing in both counties. The ratio of Pe20 in Providence vs Worcester County census tracts was 2.2 (95% confidence interval = 1.8, 2.7), after adjustment for differences in housing, sociodemographic, and screening characteristics. This estimate was robust to alternative regression methods and sensitivity analyses.
Massachusetts policy, which requires lead paint abatement of children's homes and places liability for lead paint poisoning on property owners, may have substantially reduced childhood lead poisoning in that state.
本研究调查了一项为期22年的家庭铅涂料危害消除积极计划对马萨诸塞州儿童铅中毒的影响。
采用小区域分析方法,比较了马萨诸塞州伍斯特县(n = 27,590)和罗德岛州普罗维登斯县(n = 19,071)儿童的血铅筛查水平。数据按普查区进行汇总。
尽管两县20世纪50年代以前建造的房屋比例相似,但普罗维登斯县普查区儿童铅中毒(血铅水平≥20微克/分升[Pe20])的比例平均比伍斯特县普查区高3倍(分别为3.2%和0.9%,P <.0001)。在对住房、社会人口统计学和筛查特征的差异进行调整后,普罗维登斯县与伍斯特县普查区的Pe20比值为2.2(95%置信区间 = 1.8, 2.7)。该估计值对替代回归方法和敏感性分析具有稳健性。
马萨诸塞州的政策要求对儿童家庭中的铅涂料进行清除,并将铅涂料中毒的责任归咎于业主,这可能已大幅降低了该州儿童铅中毒的发生率。